Medical Diagnostic Laboratories - a CLIA certified infectious disease laboratory with multiple state licenses specializing in PCR technology.

Antigen Discovery Division

Publications

1. McCool TL, Hoey JG, Montileone F, Goldenberg HB, Mordechai E, Adelson ME. 2008. Discovery and analysis of Bartonella henselae antigens for use in clinical serological assays. Diagn Microbiol Infect Dis, 60(1):17-23.

2. Loa CC, Mordechai E, Tilton RC, Adelson ME. 2006. Production of recombinant Bartonella henselae 17 kDa protein for antibody-capture enzyme-linked immunosorbent assay. Diagn Microbiol Infect Dis,
55(1):1-7.

3. Mogilyansky E, Loa CC, Adelson ME, Mordechai E, Tilton RC. 2004. Comparison of western immunoblots and the C6 Lyme antibody test for the laboratory detection of Lyme disease. Clin Diagn Lab Immunol, 11(5):924-929.

4. Loa CC, Adelson ME, Mordechai E, Raphaelli I, Tilton RC. 2004. Serological diagnosis of human babesiosis by IgG enzyme-linked immunoabsorbent assay. Curr Microbiol, 49:385-389.

5.Hoey JG, Valois-Cruz F, Goldenberg H, Voskoboynik Y, Pfiffner J, Mordechai E, and Adelson ME. Development of an IgM capture-based ELISA for detection of acute infection with Bartonella henselae.
Clin Vac Immun, 16(2): 282-284.

Abstracts & Presentations

1. Loa CC, Adelson ME, Mordechai E, Raphaelli I, Tilton RC. Antibody-capture enzyme-linked immunosorbent assay for human babesiosis. American Society for Microbiology 104th General Meeting, New Orleans, LA, May 23-27, 2004.

2. McCool TL, Loa CC, Mordechai E, Adelson ME. Identification of antigenic Bartonella henselae proteins. American Society of Microbiology 105th General Meeting, Atlanta, GA, June 5–9, 2005.

3. Loa CC, Mordechai E, Tilton RC, Adelson ME. Purification and antigenicity of Bartonella henselae 17 kDa
protein expressed in Escherichia coli. American Society of Microbiology 105th General Meeting, Atlanta, GA, June 5–9, 2005.

4. Loa CC, Valois-Cruz F, Goldenberg H, Mordechai E, Tilton RC, Adelson ME. Detection of human parvovirus-specific antibodies by VP1 and VP2 protein-based serological assays. 22nd Clinical Virology Symposium, Clearwater Beach, FL, April 30 - May 3, 2006.

5. Mogilyansky E, Manderbaugh K, Mason R, Mordechai E, Adelson ME. Comparison of automated ELISA-based clinical virology assays on the Mago Plus Aptus automated EIA processor and the Nexgen Four. 22nd Clinical Virology Symposium, Clearwater Beach, FL, April 30 - May 3, 2006.

6. McCool TL, Montileone FL, Goldenberg HB, Loa CC, Mordechai E, Adelson ME. Discovery of potential
Bartonella henselae antigenic proteins using a two-dimensional proteomic approach. 106th American Society of Microbiology General Meeting, Orlando, FL, May 21-25, 2006.

7. Valois-Cruz F, Loa CC, Mordechai E, Tilton RC, Adelson ME. Experiences on the development of continuous in vitro culture for Babesia microti. 106th American Society of Microbiology General Meeting, Orlando, FL, May 21-25, 2006.

8. Goldenberg HB, Valois-Cruz F, Hoey JH, Mordechai E, Adelson ME. Identification of Babesia microti antigens for use in a diagnostic assay. 107th American Society of Microbiology General Meeting, Toronto Canada, May 21-25, 2007.

9. Venit H, Valois-Cruz F, Hoey J, Mordechai E, Adelson ME. Identification of Babesia microti antigens for use in diagnostic test. 107th American Society for Microbiology General Meeting, Toronto, Canada, May 21-25, 2007.

10. Brunner M, Gallagher GE, Valois-Cruz F, Buchan R, Hoey JG, Mordechai E, Adelson ME. Cambridge
Healthtech Institute’s second annual Baculovirus Technology Meeting, Boston, MA, September 19-20, 2007.

11. Huang LP, Adelson ME, Mordechai E, Hoey JG. IgG serological assay for the detection of Bartonella henselae exposure. 109th General Meeting of the American Society for Microbiology, Philadelphia, PA. May 17-21, 2009.

Antimicrobial Resistance Division

Publications

1. Gygax SE, Schuyler JA, Kimmel LE, Trama JP, Mordechai E, Adelson, ME. 2006. Erythromycin and clindamycin resistance in Group B Streptococcal clinical isolates. Antimicrob Agents Chemother,
50(5):1875-7.

2. Gygax SE, Schuyler JA, Trama JP, Mordechai E, Adelson ME. 2007. The detection of erythromycin and clindamycin resistance genes in both Group B Streptococcal clinical isolates and cervicovaginal/rectal swabs. Microb Drug Resist, 13(2):119-123.

3. Vermitsky JP, Self MJ, Chadwick SG, Trama JP, Mordechai E, Adelson ME. 2007. A survey of vaginal flora Candida species isolates from women of different age groups by use of species-specific PCR detection. J Clin Microbiol, 46(4):1501-1503.

4. Gygax, S.E., Vermitsky, J.-P., Self, M.J., Chadwick, S.G., Mordechai, E., Adelson, M.E., and Trama, J.P. 2008. Antifungal Resistance of Candida glabrata Vaginal Isolates and the Development of a qRT-PCR-based Azole Susceptibility Assay. Antimicrob. Agents Chemother. 52(9): 3424-3426.

5. Gygax SE, Vermitsky JP, Self MJ, Mordechai E, Adelson ME, Trama JP. 2008. Antifungal resistance in vaginal Candida clinical isolates. Antimicrob Agents Chemother, manuscript under review.

6.Prasad, A., Mordechai, E., Adelson, M.E., and Gygax, S.E. 2009. PBP4 Polymorphisms Generate Penicillin Tolerance in Group B Streptococcus. Nature Medicine. Manuscript in preparation.

2. Vermitsky, J.-P., Self, M.J., Chadwick, S.G., Katiyar, S.K., Mordechai, E., Adelson, M.E., Edlind, T.D., and Gygax, S.E. 2009. cAMP-PKA kinase Tpk3 negatively regulates Candida glabrata Pdr1. Antimicrob. Agents Chemother. Manuscript in preparation.

1. Vermitsky, J-P., Chadwick, S.G., Self, M.J., Mordechai, E., Adelson, M.E., Nickels, J.T. Jr., and Gygax, S.E. 2009. CgUpc2 is the master regulator of ergosterol biosynthetic genes in Candida glabrata. Antimicrob. Agents Chemother. Manuscript in preparation.

Abstracts & Presentations

1. Gygax SE, Schuyler JA, Trama JP, Mordechai E, Adelson ME. Erythromycin and clindamycin resistance in Group B Streptococcus clinical isolates. 45th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington DC, December 16- 19, 2005.

2. Gygax SE, Prasad A, Schuyler JA, Trama JP, Mordechai E, Adelson ME. Penicillin tolerance in Group B Streptococcus. 46th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA. September 26-30, 2006.

3. Gygax SE, Schuyler JA, Trama JP, Adelson ME. A novel β-hemolysin/cytolysin expression phenotype in Group B Streptococcal clinical isolates. 107th American Society of Microbiology General Meeting, Toronto, Canada, May 21-25, 2007.

4. Gygax SE, Prasad A, Schuyler JA, Trama JP, Mordechai E, Adelson ME. Penicillin tolerance in Group B Streptococcus. 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, September 17-20, 2007.

5. Edlind TD, Vermitsky JP, Pfaller M, Gygax SE, Katiyar S. Molecular mechanisms behind flucytosine resistance and azoleflucytosine antagonism in Candida glabrata. 9th American Society for Microbiology Conference on Candida and Candidiasis, Jersey City, NJ. March 24-28, 2008.

6. Katiyar S, Vermitsky JP, Gygax SE, Edlind TD. Anatomy of Candida glabrata PdR1, master regulator of azole resistance: evidence for activation by MAP kinase SIt2. 9th American Society for Microbiology Conference on Candida and Candidiasis, Jersey City, NJ. March 24-28, 2008.

7. Vermitsky JP, Self MJ, Katiyar S, Mordechai E, Adelson ME, Edlind TD, Gygax SE. The cAMP protein kinase a signal transduction pathway negatively regulates Pdr1, the master regulator of azole resistance in Candida glabrata. 9th American Society for Microbiology Conference on Candida and Candidiasis, Jersey City, NJ. March 24-28, 2008.

8. Hilbert DW, Paulish TE, Libby EK, Pascal KE, Mordechai E, Adelson ME, Gygax SE, Trama JP. O Serotype, Virulence Factors, Plasmid Replicons, and Antibiotic Resistance of Rectal and Cervico-vaginal Escherichia coli Isolates. 108th American Society for Microbiology General Meeting. Boston, MA. June 1-5, 2008.

9. Vermitsky JP, Katiyar S, Gygax SE, Edlind TD. Multidrug resistance transcription factor Pdr1 is activated by MAP kinase Slt2 and repressed by protein kinase A Tpk3 in the opportunistic yeast Candida glabrata. 2008 Yeast Genetics and Molecular Biology Meeting. Toronto, Canada. July 22-27, 2008.

10. Prasad A, Mordechai E, Adelson ME, Gygax SE. Penicillin tolerance in Group B Streptococcus. 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, DC. October 25-28, 2008.

11. Prasad A, Basu P, Mordechai E, Adelson ME, Gygax SE.. PBP4 Polymorphisms Generate Penicillin Tolerance in Group B Streptococcus. 109th American Society for Microbiology General Meeting. Philadelphia, PA. May 17-21, 2009.

12. Vermitsky JP, Self MJ, Chadwick SG, Katiyar SK, Edlind TD, Gygax SE. 2009. cAMP-PKA kinase Tpk3 negatively regulates Candida glabrata Pdr1. 109th American Society for Microbiology General Meeting. Philadelphia, PA. May 17-21, 2009.

13. Chadwick SG, Mordechai E, Adelson ME, and Gygax SE. Susceptibility profiles of community-associated MRSA isolates from cervicovaginal swab samples. 49th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, CA. September 12-15, 2009.

Molecular and Cellular Biology Division

Publications

1. Hilbert D, Paulish T, Mordechai E, Adelson ME, Gygax SE, and Trama JP. 2009. Antimicrobial non-susceptibility of cervico-vaginal and rectal Escherichia coli isolates is associated with phylogeny and plasmid carriage. Eur J Clin Microb Infect Dis. 28(11): 1399-403.

2. Hilbert DW, Paulish TE, Mordechai E, Adelson ME, and Trama JP. 2008. O serogroups, phylogeny, and virulence factors of cervicovaginal and rectal Escherichia coli isolates. Eur J Clin Microb Infect Dis. 27(12): 1265-8.

3. Libby EK, Pascal KE, Mordechai E, Adelson ME, Trama JP. 2008. Atopobium vaginae triggers an innate immune response in an in vitro model of bacterial vaginosis. Microb Infect, 10(4):439-446.

4. Hilbert DW, Pascal KE, Libby EK, Mordechai E, Adelson ME, Trama JP. 2008. Uropathogenic Escherichia coli dominantly suppresses the innate immune response of bladder epithelial cells by a lipopolysaccharide- and Toll-like receptor 4-independent pathway. Microb Infect, 10(2):114-21.

5. Trama JP, Pascal KE, Zimmerman JA, Self MJ, Mordechai E, Adelson ME. 2008. Rapid detection of Atopobium vaginae and association with organisms implicated in bacterial vaginosis. Mol Cell Probes, 22(2):96-102.

6. Trama JP, Pascal KE, Zimmerman JA, Self MJ, Mordechai E, Adelson ME. 2007. Identification and genotyping of Molluscum Contagiosum virus from genital swab samples by Real-Time PCR and Pyrosequencing. J Clin Virol, 40(4):325-329.

7. Trama JP, Adelson ME, Raphaelli I, Mordechai E. 2005. Detection of Candida species in vaginal samples in a clinical laboratory setting. Infect Dis Obstet Gynecol, 13(2):63-7.

8. Trama JP, Mordechai E, Adelson ME. 2005. Detection and identification of Candida species associated with candida vaginitis by Real- Time PCR and Pyrosequencing. Mol Cell Probes, 19(2):145-52.

9. Trama JP, Mordechai E, Adelson ME. 2005. Detection of Aspergillus fumigatus and a mutation that confers reduced susceptibility to itraconazole and posaconazole by Real-Time PCR and Pyrosequencing. J Clin Microbiol. 43(2):906-8.

Abstracts & Presentations

1. Hilbert DW, Paulish TE, Mordechai E, Adelson ME, and Trama JP. Uropathogenic Escherichia coli inhibits the activity of nuclear-localized NF-kB to obscure a toll-like receptor-independent inflammatory stimulus. 109th General Meeting of the American Society for Microbiology, Philadelphia, PA, May 17-21, 2009.

2. Hilbert DW, Paulish TE, Mordechai E, Adelson ME, Trama JP. 2008. O serogroups, phylogeny, and virulence factors of cervicovaginal and rectal Escherichia coli isolates. Eur J Clin Microbiol Infect Dis. 27(12):1265-8.

3. Libby EK, Pascal KE, Mordechai E, Adelson ME, Trama JP. 2008. Atopobium vaginae triggers an innate immune response in an in vitro model of bacterial vaginosis. Microbes Infect. 10(4):439-46.

4. Hedges SR, Smith WL, Kaunitz AM, Adelson ME, Dorak MT, Mordechai E, Trama JP. Variations in distribution of fastidious vaginal microorganisms in a general gynecologic population. 35th Annual Scientific Meeting of the Infectious Diseases Society for Obstetrics and Gynecology, Seattle, WA, August 14-16, 2008.

5. Hilbert DW, Paulish TE, Libby EK, Pascal KE, Mordechai E, Adelson ME, Gygax SE, Trama JP. O serotypes, virulence factors, plasmid replicons and antibiotic resistance of rectal and cervicovaginal Escherichia coli isolates. 108th American Society for Microbiology General Meeting, Boston, MA. June 1-5, 2008.

6. Stemmer SM, Adelson ME, Mordechai E, Trama JP. Detection of human papillomavirus in U. S. women using Real-Time PCR: Prevalence and genotype distribution. American College of Obstetricians and Gynecologists, New Orleans, LA. May 3-7, 2008.

7. Stemmer SM, Adelson ME, Mordechai E, Trama JP. Detection rates of Trichomonas vaginalis, in different age groups, using Real-Time PCR. American College of Obstetricians and Gynecologists 56th Annual Clinical Meeting, New Orleans, LA. May 3-7, 2008.

8. Trama JP, Hilbert DW, Pascal KE, Libby EK, Mordechai E, Adelson ME. Uropathogenic E. coli subverts innate immune function of bladder epithelial cells. Experimental Biology 2008, San Diego, CA. April 5-9, 2008.

9. Hilbert DW, Pascal KE, Mordechai E, Adelson ME, Trama JP. Uropathogenic E.coli subverts innate immune function of bladder epithelial cells. 107th American Society for Microbiology General Meeting, Toronto, Canada, May 21-25, 2007.

10. Trama JP, Libby EK, Mordechai E, Adelson ME. Cervicovaginal epithelial cell cytokine production in response to microorganisms associated with bacterial vaginosis. The 94th Annual Meeting of the American Association of Immunologists, Miami Beach, Florida, May 18-22, 2007.

11. Trama JP, Zimmerman JA, Mordechai E, Adelson ME. Detection of the Chlamydia trachomatis L serovars that cause Lymphogranuloma venereum by Real-Time PCR. Association for Molecular Pathology 2006 Annual Meeting, Orlando, FL, November 16-19, 2006.

12. Adelson ME. Atopobium vaginae, a potential indicator for bacterial vaginosis? Infectious Diseases Society for Obstetrics and Gynecology 33rd Annual Scientific Meeting, Monterey, CA, August 2-5, 2006.

13. Trama JP, Pascal KE, Mordechai E, Adelson ME. Real-Time PCR detection of Atopobium vaginae and association with organisms implicated in the development of bacterial vaginosis. 106th American Society of Microbiology General Meeting, Orlando, FL, May 21-25, 2006.

14. Trama JP, Libby EK, Gygax SE, Mordechai E, Adelson ME. Differential induction of pro-inflammatory cytokines by vaginal and cervical epithelial cells in response to Group B Streptococci. Immunology 2006, Boston, MA, May 12-16, 2006.

15. Trama JP, Libby EK, Gygax SE, Mordechai E, Adelson ME. Host, pathogen, and drug host, pathogen, and drug Interactions in an in vitro model of vaginal candidiasis. 8th Annual American Society of Microbiology Conference on Candida and Candidiasis, Denver, CO, March 13-17, 2006.

16. Trama JP, Mordechai E, Adelson ME. Detection of Molluscum Contagiosum virus by Real-Time PCR and Pyrosequencing. American Society of Microbiology 105th General Meeting, Atlanta, GA, June 5–9, 2005.

17. Trama JP, McReynolds JR, Mordechai E, Stemmer SM, Adelson ME. Sequencing the genome of Atopobium vaginae, a possible indicator of bacterial vaginosis. American College of Obstetricians and Gynecologists 53rd Annual Clinical Meeting, San Francisco, CA, May 7–11, 2005.

18. Trama JP, Mordechai E, Adelson ME. Novel Real-Time PCR and Pyrosequencing technique for the detection of Aspergillus fumigatus and a mutation that confers triazole resistance. American Society for Microbiology 104th General Meeting, New Orleans, LA. May 23-27, 2004.

19. Mordechai E, Trama JP, Raphaelli I, Adelson ME. Prevalency of Candida species associated with candida vaginosis in the United States. American Society for Microbiology 104th General Meeting, New Orleans, LA, May 23-27, 2004.

20. Trama JP, Stemmer SM, Mordechai E, Adelson ME. Analyzing Candida albicans gene mutations that contribute to azole resistance by Pyrosequencing. American College of Obstetricians and Gynecologists 52nd Annual Clinical Meeting, Philadelphia, PA, May 1-5, 2004.

21. Trama JP, Stemmer SM, Mordechai E, Adelson ME. Novel technique for identification of vulvovaginal candidiasis by Real-Time PCR and Pyrosequencing. American College of Obstetricians and Gynecologists 52nd Annual Clinical Meeting, Philadelphia, PA, May 1-5, 2004.

Molecular Diagnostics Development Division

Publications

1. Biggs C, Walsh P, Overmyer CL, Gonzalez D, Feola M, Mordechai E, Adelson ME, and Iacono KT. 2010. Performance of influenza rapid antigen testing in influenza in emergency department patients.
Emerg Med J. 27(1): 5-7.

2. Meer-Scherrer L, Adelson ME, Mordechai E, Tilton RC. 2006. Neuroborreliosis associated with Alzheimer’s disease. Curr Microbiol, 52(4):330-2.

3. Drisko J, Bischoff B, Giles C, Adelson ME, Rao RV, McCallum R. 2005. Evaluation of 5 probiotic products for bacteria by DNA extraction and PCR analysis. Dig Dis Sci, 50(6):1113-7.

4. Adelson ME, Feola M, Trama JP, Tilton RC, Mordechai E. 2005. Simultaneous detection of herpes simplex virus types 1 and 2 by Real-Time PCR and Pyrosequencing. J Clin Virol, 33(1):25-34.

5. Adelson ME, Rao RV, Tilton RC, Cabets K, Eskow E, Fein L, Occi JL, Mordechai E. 2004. Prevalence of Borrelia burgdorferi, Bartonella species, Babesia microti, and Anaplasma phagocytophila in Ixodes scapularis collected in northern New Jersey. J Clin Microbiol, 42:2799-2801.

6. Meer-Scherrer L, Adelson ME, Mordechai E, Lottaz B, Tilton RC. 2004. Babesia microti infection in Europe. Curr Microbiol, 48(6):435-7.

7. Eskow E, Rao RV, Mordechai E. 2001. Concurrent infection of the central nervous system by Borrelia burgdorferi and Bartonella henselae: Evidence for a novel tick-borne disease complex. Arch Neurol, 58:1357-1363.

8. Eskow E, Adelson ME, Rao RV, Mordechai E. 2003. Evidence for disseminated Mycoplasma fermentans in New Jersey residents with antecedent tick attachment and subsequent musculoskeletal symptoms. J Clin Rheumatol, 9:77-87.

9. Tilton RC. 2003. New tests for Lyme disease. Clin Microbiol Newsl, 25(19):145-149.

Abstracts & Presentations

1. Biggs C, Overmyer CL, DeSalvia L, Gonzalez D, Gofman L, Feola M, Iacono KT, Mordechai E, Adelson ME. Geographic distribution of pediatric respiratory infections: A bi-coastal analysis. Molecular Medicine, Lake Buena Vista, FL. March 27- 30, 2008.

2. Biggs C, Overmyer CL, DeSalvia L, Gonzalez D, Gofman L, Feola M, Iacono KT, Mordechai E, Adelson ME. A comparison of nasopharyngeal and midturbinate region sampling for the detection of respiratory infections. 24th Clinical Virology Symposium, Daytona Beach, FL. April 27-30, 2008.

3. Walsh P, Lim-Overmyer CL, Gofman L, DeSalvia L, Gonzalez D, Feola M, Nguyen A, Pusavat J, Nguyen TA, Pham K, Michaelson S, Iacono KT, Mordechai E, Adelson ME. Comparison of three nasal collection specimen methods for the detection of pediatric respiratory infectious disease. Association for Molecular Pathology 2007 Annual Meeting, Los Angeles, California, November 7-10, 2007.

4. Balashov S, Mordechai E, Adelson ME. Development of a new test for cystic fibrosis mutation screening. Association for Molecular Pathology 2007 Annual Meeting, Los Angeles, CA, November 7-10, 2007.

5. Zimmerman J, Feola M, Mordechai E, Adelson ME. Detection and quantification of Actinomyces israelli in cervicovaginal specimens by Real-Time PCR. 107th American Society for Microbiology General Meeting, Toronto, Canada, May 21-25, 2007.

6. Mason R, Feola M, Mordechai E, Adelson ME. Hepatitis B virus subtype determination through Pyrosquencing. 107th American Society for Microbiology General Meeting, Toronto, Canada, May 21-25, 2007.

7. Walsh P, Overmyer CL, Gofman L, Nguyen T, Michaelson S, Pusavat J, DeSalvia L, Gonzalez D, Feola M, Nguyen KA, Iacono KT, Mordechai E, Adelson ME. Pediatric respiratory infectious disease analysis: UTM-RT versus flocked swab nasal collections. The 23rd Clinical Virology Symposium, Clearwater, Florida, April 29-May 2, 2007.

8. Biggs C, Overmyer CL, Gofman L, DeSalvia L, Gonzalez D, Feola M, Iacono KT, Mordechai E, Adelson ME. Prevalence of pediatric respiratory infections in a suburban Philadelphia hospital. The 23rd Clinical Virology Symposium, Clearwater, Florida, April 29-May 2, 2007.

9. Valois-Cruz F, Loa CC, Mordechai E, Tilton RC, Adelson ME. Simultaneous detection and identification of Bartonella henselae and Bartonella quintana by a duplex Real-Time PCR and Pyrosequencing assay. Association for Molecular Pathology 2006 Annual Meeting, Orlando, FL, November 16-19, 2006.

10. Entwistle J, Feola M, Rao RV, Zimmerman JA, Trama JP, Mordechai E, Adelson ME. Molecular detection of a plurality of pathogens in UTM-RT. 9th Annual European Society for Clinical Virology Meeting, Birmingham, United Kingdom, September 3-6, 2006. 20

11. Entwistle J, Feola M, Mordechai E, Adelson ME. Real-Time PCR detection of polyomaviruses BK and JC in Urine. 9th Annual European Society for Clinical Virology Meeting, Birmingham, United Kingdom, September 3-6, 2006.

12. Feola M, Nguyen TT, Entwistle J, Zimmerman JA, Mordechai E, Adelson ME. Trichomonas vaginalis sequence heterogeneities may necessitate multiple Real-Time PCR detection assays.106th American Society of Microbiology General Meeting, Orlando, FL, May 21-25, 2006.

13. Nguyen T, Feola M, Mordechai E, Stemmer SM, Adelson ME. Bacterial vaginosis: Development of a Real-Time PCR assay for the detection of Mobiluncus species and Bacteroides fragilis. Annual Clinical Meeting of the American College of Obstetricians and Gynecologists, Washington DC, May 8-10, 2006.

14. Lim C, Kimmel L, Nuesa J, Mordechai E, Stemmer SM, Adelson ME. Robotic PCR detection of human papillomavirus genotypes in cervicovaginal swab and urine specimens. 54th Annual Clinical Meeting of the American College of Obstetricians and Gynecologists, Washington DC, May 8-10, 2006.

15. Adelson ME, Rao RV, Trama JP, Mordechai E. Evaluation of UTM-RT for the molecular detection of a plurality of OB/GYN related pathogens. 45th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy Meeting, Washington DC, December 16-19, 2005.

16. Feola M, Laskowski R, Choi D, Trama JP, Mordechai E, Adelson ME. Detection and confirmation of the urogenital Mycoplasmas, Ureaplasma urealyticum, Mycoplasma hominis, and Mycoplasma genitalium by Real-Time PCR and Pyrosequencing. American Society of Microbiology 105th General Meeting, Atlanta, GA, June 5–9, 2005.

17. Naurath EF, Mohr EL, Adelson ME, Stemmer SM, Mordechai E, Trama JP. Detection and quantification of Gardnerella vaginalis by Real-Time PCR. American College of Obstetricians and Gynecologists 53rd Annual Clinical Meeting, San Francisco, CA, May 7–11, 2005.

18. Adelson ME, Feola M, Mordechai E. Development of a Real-Time PCR assay for the simultaneous detection of herpes simplex virus types 1 and 2 with confirmation by Pyrosequencing technology. American Society for Microbiology 104th General Meeting, New Orleans, LA, May 23-27, 2004.

19. Adelson ME, Feola M, Stemmer SM, Mordechai E. Diagnosis of Neisseria gonhorrhea, Chlamydia trachomatis and Trichomonas vaginalis by Real-Time PCR. American College of Obstetricians and Gynecologists 52nd Annual Clinical Meeting, Philadelphia, PA, May 1-5, 2004.

20. Drisko J, Bischoff B, Giles C, Adelson ME, Rao RV, McCallum R. Evaluation of 5 probiotic products for bacteria by DNA extraction and PCR analysis. Digestive Disease Week 2003, American Gastroenterological Association, Orlando, FL, May 17-22, 2003.

21. Mordechai E, Adelson ME, Cabets K, Eskow E, Fein L, Occi J. Pivotal role of PCR in the detection of coinfections. 15th International scientific conference on Lyme disease and other tick-borne disorders, Farmington, CT, April 6-7, 2002.

Pharmacogenomics Division

Publications

1. Morgan J, McCourt P, Rankin L, Swain E, Rice LM, and Nickels Jr. JT. 2009. Altering sphingolipid
     metabolism in yeast cells lacking the amphiphysin ortholog, Rvs161, re-initiates sugar transporter
     endocytosis. Eukaryot Cell, 8(5): 779-789.

2. McCourt P, Morgan J, Nickels Jr. JT. 2009. Stress-induced ceramide-activated protein phosphatase can     compensate for loss of amphipysin-like activity in Saccharomyces cerevisiae and functions to reinitiate     endocytosis. J Biol Chem, 284(18): 11930-11941.

3. McCourt P, Morgan J, Nickels Jr JT. 2009. Stress-induced ceramide-activated protein phosphatase can     compensate for loss of amphiphysin-like activity in Saccharomyces cerevisiae and functions to reinitiate     endocytosis. J Biol Chem. In press.

Abstracts & Presentations

1. McCourt PC, Nickels JT. Molecular Analysis of the Candida albicans Arv1 Ortholog of Saccharomyces     cerevisiae. American Society of Microbiology Meeting. Philadelphia, PA. May 17-21, 2009.

2. Villasmil ML, Bower M, Ansbach A, Nickels JT. The putative lipid transporter, Arv1, is required for mating in     Saccharomyces cerevisiae. Yeast Genetics and Molecular Biology Meeting, Toronto, Canada. July 22-27,     2008.

3. Gallo C, Bower M, Shirzadi R, Nickels JT. The SRE-dependant and –independent transcriptional regulation
    of sterol gene expression in Saccharomyces cerevisiae. Yeast Genetics and Molecular Biology Meeting,     Toronto, Canada. July 22-27, 2008.
4. Rice LM, Nickels JT. PP2A is required for SREBP2 transcription factor activity. Keystone Symposia –     Metabolism and Cardiovascular Risk. September 23-28, 2008