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Antigen Discovery Division
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| Personnel |
| John G. Hoey, Ph.D. - Antigen Discovery Team Leader |
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Ph.D. in Cell and Molecular Biology from the City University of NY Graduate School and University Center.
- Graduate work was done under the mentorship of Ray H. Gavin, Ph.D., and focused on the identification and characterization of a non-muscle contractile system associated with basal bodies in Tetrahymena.
- Postdoctoral fellowship at the National Heart, Lung, and Blood Institute of the National Institutes of Health. Postdoctoral project involved the cloning and expression of Myosin I Heavy Chain Kinase from Acanthamoeba.
- Sr. Research Associate position in the Laboratory of Experimental Pathology at West Virginia University School of Medicine. Research involved the identification and cloning of the heavy metal response gene Metallothionein (MT)-3 from normal and carcinoma-derived human kidney cells. Originally named growth inhibitory factor (GIF) and thought to be a brain-specific member of this gene family, MT-3 is intriguing because of its ability to inhibit the growth of neuronal cells in culture, and because of its deficiency in Alzheimer’s diseased (AD) brain tissue. This deficiency has been proposed to be involved in the formation of neurofibrillary tangles (NFT) in the neuropathology of AD.
- Previous positions as Sr. Scientist within the Gene Isolation Laboratory at NaPro Biotherapeutics (now Tapestry Pharmaceuticals), and Research Assistant Professor at the Mary Babb Randolph Cancer Center of West Virginia University School of Medicine.
- Currently investigating the human antibody response to Bartonella henselae antigens.
- Recently developed an IgM ELISA for serological diagnosis of acute infection with Bartonella henselae.
- Oversee, advise, and direct all projects being done by the Antigen Discovery team.
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| Hannah Goldenberg, Ph.D. - Immunology Research Associate |
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Ph.D. in Immunology from the University of Pennsylvania (Advisor: Dr. Jeffrey N. Weiser). Dissertation: “The effect of human antibody specific for phosphorylcholine on Streptococcus pneumoniae and Haemophilus influenzae”.
- Examined the effectiveness of purified human antibody to phosphorycholine expressed on Streptococcus pneumoniae and Haemophilus influenzae. Studied the in vitro effect of human anti-phosphorylcholine antibody on both S. pneumoniae and H. influenzae as well as the in vivo effect of the antibody against S. pneumoniae.
- Worked with Drs. M. Preston and G. Pier at the Channing Laboratory on the production of humanized monoclonal antibodies to the LPS of Pseudomonas aeruginosa.
- Extensive experience with Immunology, Molecular Biology/Microbiology, and Animal Modeling laboratory techniques.
- Involved in the development of new clinical assays for the Antigen Discovery team.
- Recently developed IgG and IgM ELISAs for serological diagnosis of infection with Babesia microti.
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| Lisa P. Huang, Ph.D. - Research Scientist |
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Research Associate, Weill Medical College of Cornell University, NYC. Conducted research on limb regeneration, cell differentiation, and cancer pharmacology.
- Postdoctoral Fellow, Stanford University School of Medicine, Palo Alto, CA. Studied in vivo and in vitro functions of Granulysin to develop novel antibiotics and new oncogenic therapeutics.
- Ph.D. in Molecular Virology, Purdue University, West Lafayette, IN.
- B.S., University of Science and Technology of China (USTC).
- Membership: American Association of Immunologists; American Society for Virology; and RNA Society.
- Award: Andrews Fellowship; Travel Award for American Society for Virology Annual Meeting.
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| Crystal Mazur, M.S. |
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- M.S. from the University of Florida in Medical Sciences. Thesis: Optimization of methods for phage display using single-chain variable fragment phagemid libraries.
- B.S. from the University of Florida, magna cum laude, in Microbiology and Cell Sciences with a minor in Chemistry. Thesis: Characterization of temperature sensitive Vaccinia virus mutants from E11 and E6 complementation groups.
- Currently developing diagnostic assays for cancer detection.
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Office:
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877.269.0090
609.570.1000
609.570.1050 |
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Medical Diagnostic Laboratories, L.L.C. |
2439 Kuser Road |
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Hamilton, NJ 08690 |
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Copyright © 1997-2006 |
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