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Virology Division
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| Publications |
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Aubert M, Blaho JA. 2003. Viral oncoapoptosis of human tumor cells. Gene Therapy, 10:1437-1445.
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Goodkin M, Ting A, Blaho JA. 2003. NF-kB is required for apoptosis prevention during HSV-1 infection. J Virol, 77:7261-7280.
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Sanfilippo CM, Chirimuuta FNW, Blaho JA. 2004. HSV-1 IE gene expression is required for the induction of apoptosis in human epithelial HEp-2 cells. J Virol, 78:224-239.
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Sanfilippo CM, Lombardozzi RC, Chirimuuta FNW, Blaho JA. 2004. HSV-1 infection is required to produce ICP27 immunoreactive triplet forms when ribosomal amino-acyl-tRNA translocation is blocked by CHX. Virology, 324:554-566.
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Yedowitz J, Kotsakis A, Schlegel E, Blaho J. 2005. Nuclear localization of the HSV-1 tegument proteins VP13/14, vhs, and VP16 precede VP22-dependent microtubule reorganization and VP22 nuclear import. J Virol, 79:4730-4743.
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Nguyen ML, Kraft RM, Blaho JA. 2005. African green monkey kidney Vero cells require de novo protein synthesis for efficient HSV-1 dependent apoptosis. Virology, 336:274-290.
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Yedowitz JC, Blaho JA. 2005. HSV-2 modulates apoptosis and stimulates NF-kB during infection of human epithelial HEp-2 cell. Virology, 342:297-310.
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Emre NC, Ingvarsdottir K, Wyce A, Wood A, Krogan NJ, Henry KW, Li K, Marmorstein R, Greenblatt JF, Shilatifard A, Berger SL. 2005. Maintenance of low histone ubiquitylation by Ubp 10 correlates with telomere-proximal Sir2 association and gene silencing. Mol Cell, 17:585-594.
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Chi JH, Harley CA, Mukhopadhyay A, Wilson DW. 2005. The cytoplasmic tail of herpes simplex virus envelope glycoprotein D binds to the tegument protein VP22 and to capsids. J Gen Virol, 86:253-261.
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Ingvarsdottir K, Krogan NJ, Emre NC, Wyce A, Thompson NJ, Emili A, Hughes TR, Greenblatt JF, Berger SL. 2005. Free in PMC H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. Mol Cell Biol, 25:1162-1172.
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Nathan D, Ingvarsdottir K, Sterner DE, Bylebyl GR, Dokmanovic M, Dorsey JA, Whelan KA, Krsmanovic M, Lane WS, Meluh PB, Johnson ES, Berger SL. 2006. Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications. Genes Dev, 20:966-976.
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Sanfilippo CS, Blaho JA. 2006. ICP0 gene expression is a HSV-1 apoptotic trigger. J Virol, 80:6810-6821.
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Kraft RM, Nguyen ML, Yang XH, Thor AD, Blaho JA. 2006. Caspase 3 activation during herpes simplex virus 1 infection. Virus Res, 120:163-175.
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Aubert, M, Pomeranz LE, Blaho JA. 2007. Herpes simplex virus blocks apoptosis by precluding mitochondrial cytochrome c release independent of caspase activation in infected human epithelial cells. Apoptosis, 12:19-35.
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Nguyen ML, Blaho JA. 2007. Apoptosis during herpes simplex virus infection. Adv Virus Res. 69:67-97.
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Morton EM, Blaho JA. 2007. Herpes simplex virus blocks Fas mediated apoptosis independent of viral activation of NF-B in human epithelial HEp-2 cells. J Interferon Cytokine Res 27:365-76.
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Nguyen ML, Kraft RM, Blaho JA. 2007. Susceptibility of cancer cells to herpes simplex virus dependent apoptosis. J Gen Virol 88:1866-75.
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Nguyen ML, Kraft RM, Aubert M, Goodwin E, Dimaio D, Blaho JA. 2007. p53 and hTERT determine sensitivity to viral apoptosis. J Virol, 81:12985-12995.
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Goodkin M, Epstein S, Asbell PA, Blaho JA. 2007. Nuclear translocation of NF-?B precedes cleavage of apoptotic death factor PARP during productive HSV-1 replication in rabbit corneal epithelial cells. Invest Ophthal Vis Sci, in press.
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Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schullinder M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, Amdrews B, Boone C Berger SL, Hieter P, Zhang Z, Brown GW, Ingles CJ, Emili A, Allis CD, Toczyski DP, Weissman JS, Greenblatt JF, Krogan NJ. 2007. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature, 446:806-810.
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Ingvarsdottir K, Edwards C, Lee MG, Lee JS, Schultz DC, Shilatifard R, Berger SL. 2007. Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae. Mol Cell Biol, 27:7856-7864.
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Cotter CR, Blaho JA. 2008. Detection of herpes simplex virus dependent apoptosis. Methods Mol Biol, In press.
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| Abstracts & Presentations |
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Nguyen ML, Aubert M, DiMiao D, Blaho JA. p53 and hTERT determine sensitivity to herpes simplex virus dependent apoptosis. 33rd Annual International Herpesvirus Workshop, Estoril, Portugal. July 27-August 1, 2008.
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