Our Research and Development department at MDL is comprised of experts in the fields of Molecular Biology, Molecular Virology, Microbiology, Immunology, and Molecular Oncology. Our main theme of research is in the field of infectious diseases with an emphasis on the use of PCR methodologies. Please find below our recent scientific publications--reprints are available upon request. Check back frequently as our research group is actively publishing.

Our Research and Development Department shall be presenting their work at the following meetings this year:
8th Annual ASM Conference on Candida and Candidiasis. March 13-17, 2006 Denver, Colorado.
	Trama, J.P., Libby, E.K., Gygax, S.E., Mordechai, E., and Adelson, M.E. Host, Pathogen, and Drug Host, Pathogen, and Drug Interactions in an In Vitro Model of Vaginal Candidiasis.
2006 22nd Clinical Virology Symposium. April 30 - May 3, 2006 Clearwater Beach, FL
	Loa, C.C., Valois-Cruz, F., Goldenberg, H., Mordechai, E., Tilton, R.C., Adelson, M.E. Detection of human parvovirus-specific antibodies by VP1 and VP2 protein-based serological assays. Mogilyansky, E., Manderbaugh, K., Mason, R., Mordechai, E., Adelson, M.E. Comparison of Automated ELISA-based Clinical Virology Assays on the Mago Plus Aptus Automated EIA Processor and the Nexgen Four.
2006 Annual Clinical Meeting (ACM) of the American College of Obstetricians and Gynecologists (ACOG). May 6-10, 2006 Washington, DC
	Nguyen, T., Feola, M., Mordechai, E., Stemmer, S., and Adelson, M.E. Bacterial Vaginosis: Development of a Real-Time PCR Assay for the Detection of Mobiluncus species and Bacteroides fragilis. Lim, C., Kimmel, L., Nuesa, J., Mordechai, E., Stemmer, S., and Adelson, M.E. Robotic PCR Detection of Human Papillomavirus Genotypes in Cervicovaginal Swab and Urine Specimens.
106th American Society of Microbiology General Meeting. May 21-25, 2006 Orlando, FL
	Trama, J.P., Pascal, K.E., Mordechai, E., Adelson, M.E. Real-time PCR Detection of Atopobium vaginae and Association with Organisms implicated in the Development of Bacterial Vaginosis. Feola, M., Nguyen, T.T., Entwistle, J., Zimmerman, J.A., Mordechai, E., Adelson, M.E. Trichomonas vaginalis Sequence Heterogeneities May Necessitate Multiple Real-Time PCR Detection Assays. McCool, T.L., Montileone, F.L., Goldenberg, H.B., Loa, C.C., Mordechai, E., Adelson, M.E. Discovery of Potential Bartonella henselae Antigenic Proteins Using a Two-Dimensional Proteomic Approach. Valois-Cruz, F., Loa, C.C., Mordechai, E., Tilton, R.C., Adelson, M.E. Experiences on the Development of Continuous In Vitro Culture for Babesia microti

	Hoey, J., Pascarelli, K., Valois-Cruz, F., Gallagher, G.E., Mordechai, E., Adelson, M.E. Cloning, sequencing, and expression of a genomic DNA clone encoding a novel IgM-reactive immunogenic peptide from Bartonella henselae.
	Hoey, J., Pascarelli, K., Valois-Cruz, F., Gallagher, G.E., Mordechai, E., Adelson, M.E. Discovery and analysis of Bartonella henselae antigens for use in clinical serological assays.
	Gygax, S.E., Schuyler, J.A., Trama, J.P., Mordechai, E., Adelson, M.E. A Novel β-hemolysin/cytolysin Expression Phenotype in Group B Streptococcal Clinical Isolates.
	Hilbert, D., Pascal, K.E., Mordechai, E., Adelson, M.E., Trama, J.P. Uropathogenic E. coli suppress innate immune response of bladder epithelial cells.
	Gygax, S.E.*, Vermitsky, J.-P.*, Self, M., Mordechai, E., Adelson, M.E., Trama, J.P. Antifungal resistance of vaginal Candida clinical isolates. (* contributed equally to the work)
	McCool, T.L., Hoey, J., Montileone, F., Loa, C.C., Goldenberg, H.B., Mordechai, E., and Adelson, M.E. Discovery and analysis of Bartonella henselae antigens for use in clinical serological assays.
	Loa, C.C., Valois-Cruz, F., Goldenberg, H., Mordechai, E., Tilton, R.C., and Adelson, M.E. Detection of Human Parovirus-Specific Antibodies by VP1 and VP2 Protein-Based Serological Assays.
	Trama, J.P., Pascal, K.E., Zimmerman, J., Self, M.F., Mordechai, E., M.E. Adelson. Methods for detection of Atopobium vaginae and association with organisms implicated in bacterial vaginosis.
	Stemmer, S.M., Adelson, M.E., Trama, J.P., Raphaelli, I., Mordechai, E. Prevalence of Neisseria gonorrhoeae, Chlamydia trachomatis, and Tricohomonas vaginalis in a clinical laboratory setting.
	Trama, J.P., Mordechai, E., and Adelson, M.E. Identification and Genotyping of Molluscum Contagiosum Virus from Genital Swab Samples by Real-time PCR and Pyrosequencing.
	Fein, L., Adelson, M.E., Mordechai, E., Iacono, K.T. Case Report of Neurosarcoidosis Associated With Evidence of Bartonella Infection. To be submitted to the Archives of Neurology, February 1st or 2nd, 2007.
	Loa, C.C., Valois-Cruz, F., Tilton, R.C., Mordechai, E., and Adelson, M.E. A duplex real-time PCR for the simultaneous detection and identification of Bartonella henselae and Bartonella quintana with confirmation by Pyrosequencing. Molecular and Cellular Probes. Submitted October 24, 2006. Currently being revised.
	Gygax, S.E., Schuyler, J.A., Trama, J.P., Mordechai, E., and Adelson, M.E. Detection of Erythromycin and Clindamycin Resistance Genes in Both Group B Streptococcal Clinical Isolates and Cervicovaginal-Rectal swabs. Submitted to Diagnostic Microbiology and Infectious Diseases, 10/09/2006, rejected. Reformatted and submitted to Microbial Drug Resistance, 10/13/2006; Review Received 11/02/2006; Shortened and resubmitted 11/14/2006.

RECENT PUBLICATIONS

	Gygax, S.E., Schuyler, J.A., Kimmel, L.E., Trama, J.P., Mordechai, E., and Adelson, M.E. Erythromycin and Clindamycin Resistance in Group B Streptococcal Clinical Isolates. (2006) 50(5): 1875-7.
	Loa, C.C., Mordechai, E., Tilton, R.C., and Adelson, M.E. (2006) Production of recombinant Bartonella henselae 17 kDa protein for antibody-capture enzyme-linked immunosorbent assay. Diagnostic Microbiology and Infectious Disease. 55(1): 1-7.
	Meer-Scherrer L., Adelson M.E., Mordechai E., and Tilton R.C. (2006) Neuroborreliosis associated with Alzheimer’s Disease. Current Microbiology , 52(4): 330-2.
	Adelson M.E., Feola M., Trama J., Tilton R.C., and Mordechai E. (2005). Simultaneous Detection of Herpes Simplex Virus Types 1 and 2 by Real-Time PCR and Pyrosequencing. Journal of Clinical Virology. 33(1): 25-34.
	Adelson M.E., Feola M., Trama J., Tilton R.C., and Mordechai E. (2005). Simultaneous Detection of Herpes Simplex Virus Types 1 and 2 by Real-Time PCR and Pyrosequencing. Journal of Clinical Virology. 33(1): 25-34.
	Trama J., Adelson M.E., Raphaelli I., and Mordechai E. (2005) Detection of Candida species in vaginal samples in a clinical laboratory setting. Infectious Diseases in Obstetrics & Gynecology, 13(2): 63-7.
	Drisko J., Bischoff B., Giles C., Adelson M.E., Rao R.-V., McCallum R. (2005) Evaluation of 5 probiotic products for bacteria by DNA extraction and PCR analysis. Digestive Diseases and Sciences, 50(6): 1113-7.